诺和诺德下一代减肥药试验结果创历史新高
Results From Novo Nordisk's Next-Gen Obesity Pill Trial Send Shares To Record

原始链接: https://www.zerohedge.com/markets/results-novo-nordisks-next-gen-obesity-pill-trial-send-shares-record

在丹麦制药公司诺和诺德 (Novo Nordisk A/S) 主办的一次投资会议上,该公司分享了他们在 I 期临床试验中使用香蜜素药丸治疗下一代肥胖症的积极成果。 服用阿霉素药丸的参与者在 12 周内体重减轻了约 13.1%,而在使用该公司现有注射药物 Wegovy 的试验中发现体重减轻了 6%。 Amycretin 利用与 Wegovy 相同的 GLP-1 激素和额外的食欲控制调节剂(胰淀素),使这种方法独一无二。 Novo 研发主管 Martín Lang Holst 确认计划于今年晚些时候开始对阿霉素进行 II 期临床测试,预计结果将于 2026 年初得出。根据古根海姆分析师 Seamus Fernandez 等专家的说法,即将推出的药物代表着巨大的增长机会 对于诺沃; 它们现值的近百分之五十可归因于这些潜在的治疗方法。 从本质上讲,最新结果凸显了 Novo 致力于推进超越传统减肥方法的肥胖管理疗法。

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原文

Shares of Danish pharmaceutical giant Novo Nordisk A/S soared to a new record high on Thursday after the company reported progress in its pill-based next-generation obesity treatment during an investor event. 

Investors cheered when Novo released the results of a Phase I trial of the amycretin pill version, which showed participants lost about 13.1% after 12 weeks. This compares to a 6% weight loss drop after 12 weeks in the trial for its injectable Wegovy drug. 

Amycretin uses the same GLP-1 hormone as other weight-loss drugs, such as Wegovy and Lilly's Zepbound. The key is that it also stimulates the hormone amylin, which regulates hunger. 

The study's results boosted Novo shares in Copenhagen by as much as 8% to 918 krone a share.

The company's head of research and development, Martin Lange Holst, expects the Phase II trial of amycretin to begin in the second half of this year. Results are expected in early 2026. 

Novo's next-generation projects are outlined in this slide. 

"Novo has made clear that the amycretin molecule likely will form the foundation of the company's rapidly growing pipeline," said Guggenheim analyst Seamus Fernandez.

Last week, Berenberg Bank analysts wrote in a note to clients that nearly half of Novo's current valuation has been built on the company's pipeline of new experimental drugs. 

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