在NASA的洁净室中发现新的细菌物种
New bacterial species discovered in NASA's cleanrooms

原始链接: https://www.nature.com/articles/d44151-025-00219-7

尽管采取了包括辐射、严格清洁和湿度控制在内的严苛消毒规程,一支国际研究团队仍在组装“凤凰号”火星探测器的美国国家航空航天局(NASA)洁净室中,发现了26种新的细菌物种。 这些顽强的微生物进化出了复杂的生存机制,以在极端环境中茁壮成长。许多细菌会产生粘性生物膜以附着在表面,而另一些则形成保护性孢子来抵御化学处理。从基因层面来看,这些细菌具备修复辐射和氧化应激所致DNA损伤的能力。 除了韧性之外,这些微生物还拥有独特的代谢特性,对人类工业具有巨大的潜力。其中几个物种能产生宝贵的天然化合物,包括抗菌聚合物、玉米黄质等抗氧化剂,以及具有抗癌特性的分子。研究人员认为,这些“极端微生物”有望成为地球医药和食品保鲜等领域中,各类新型生物分子的重要来源。

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Many bacterial species resist cleaning chemicals and cling to sterile surfaces by producing sticky films in NASA's cleanrooms. Credit: NASA/JPL-Caltech

NASA’s cleanrooms are sterilised by reducing humidity, through intense cleaning, and radiation exposure. Yet, some microbes persist in these rooms, an international research team has found1.

The team has identified 26 new bacterial species in the cleanrooms where the Phoenix Mars Lander was assembled before its lift-off.

The team, which included researcher Karthik Raman at the Indian Institute of Technology Madras in Chennai, found many bacterial species that resist cleaning chemicals and cling to sterile surfaces by producing sticky films. Many have genes that protect their DNA from radiation damage, while some have genes that help control cell repair under oxidative stress.

Several bacterial species can form spores, helping them form hard, protective shells to live through harsh treatments.

Many of these bacteria also have genes that are useful for making valuable natural compounds. For instance, Agrococcus phoenicis and Microbacterium canaveralium produce an antimicrobial polymer used in food preservation and medicine. Sphingomonas canaveralia makes zeaxanthin, an antioxidant beneficial for eye health. One bacterium makes a molecule that helps capture iron and another synthesises molecules with anticancer and antimicrobial properties.

The unique metabolic capabilities of these bacteria make them promising sources of novel biomolecules that could benefit industry on Earth, the researchers note.

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