I have the 16 bit successor, the 65816, on a variable speed expansion card in my Apple 2. I run it in 8 bit mode most of the time mostly because it works and most library code is 8 bit.
At those speeds, the chip is fast! Especially when one considers the simple model: ram clocked 1:1 with the cpu. In my case, I can run code over the 1Mhz bus, essentially turning most multi cycle ops into a single bus cycle per memory fetch.
Or, the card has a megabyte of RAM and that runs at CPU speed. (0.15 to 16 Mhz) When doing that, it is fast enough to run large programs, written in higher level languages, at a useful speed. Of course Assembly language is crazy fast.
It is a pretty fun environment to hack around in.