昨晚一个AI代理对一只老鼠进行了脑手术
Last night an AI agent performed brain surgery on a mouse

原始链接: https://twitter.com/OcanaSantero/status/2115442964574908902

昨晚,一个 AI 智能体对一只小鼠进行了脑部手术。我们给了它一张包含 19 种基因治疗载体的电子表格、一个癫痫小鼠模型、一台带摄像头的电动手术架,以及一个目标:减少癫痫发作。它选定了药物。它选定了脑区。它从三篇论文中推导出坐标。然后它驱动立体定位臂进入大脑,在通过手术架摄像头观察穿刺部位有无出血的同时,注射了 250 纳升。一名持证兽医对每个不可逆步骤进行把关,并握着物理终止开关以随时停止 AI 智能体。本帖将讲述它做了什么决定、它看到了什么,以及它拒绝让我覆盖它的那一刻。[因兴奋而当场撰写,但我已连续 18 小时在笔记本电脑前编程和协调此事,因此先简要描述,稍后会有更连贯的想法……]

Hacker News 用户讨论了一项声明,称一个 AI 代理对一只老鼠进行了脑手术。评论者质疑这是否是真正的手术,还是主要是在人类开颅后由 AI 控制的注射/针操作,且因编码错误导致人工接管。其他人辩论了动物实验的伦理,认为实验是表演性博取关注,且可能不安全,因为 AI 缺少有害操作的可靠反馈回路。一些人认为动物研究很常见,并认为 AI 最终可能改善医疗程序。讨论还涉及医疗可及性,有人担心 AI 会取代人类医生,也有人怀疑 LLM 被过度炒作。总体上,讨论围绕 AI 实际做了什么、是否合乎伦理、以及 AI 距离安全自主手术有多近。
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原文

Last night an AI agent performed brain surgery on a mouse. We gave it 19 gene therapy vectors in a spreadsheet, a mouse model of epilepsy, access to a motorize surgery rig with cameras and one goal: reduce seizures. It picked the drug. It picked the brain region. It derived the coordinates from three papers. Then it drove the stereotaxic arms into the brain and injected 250 nanolitres while watching the entry site through the rig camera for bleeding. A licensed vet gated every irreversible step and held a physical kill switch to stop the AI agent. Thread on what it decided, what it saw, and the moment it refused to let me override it. [Writing this on the spot out of excitement, but I've been 18hrs in front of my laptop coding and coordinating this, so keeping it brief and descriptive, more cohesive thoughts on this soon...]

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