It supports the COFF and ELF object file formats, for the x86 and MIPS architectures. It has been successfully used on Linux, Windows and PlayStation executables. One user report is on a commercial video game from 2009 with a ~7 MiB Windows executable written in C++: it was delinked without its C runtime library and then relinked into a new executable at a different base address, with no visible change in functionality, as a prelude to a decompilation project.
Use-cases I've demonstrated on my blog include modding, making software ports, converting executable file formats, creating libraries... I've originally built this as part of a video game decompilation project ; I've been working on this over the past 2.5 years and recently it has started gaining some users besides me.