变形金刚:生命与死亡的深层化学
Transformer: The Deep Chemistry of Life and Death

原始链接: https://nick-lane.net/books/transformer-the-deep-chemistry-of-life-and-death/

尼克·莱恩的《变形金刚》(Transformer)探讨了一个根本性问题:是什么将活细胞与非生命物质区分开来,而这种区别并非仅仅由信息就能解释。莱恩强调了克雷布斯循环——一个将无机分子转化为生命构成要素的核心代谢过程——对于理解生命深刻的内在联系至关重要。这一循环将从早期细菌到复杂生物体的各种生命形式联系起来,并将看似毫不相关的概念,如意识和死亡,联系在一起。莱恩认为,理解克雷布斯循环是理解生命作为一种化学现象的关键,它揭示了个体差异与地球生命起源宏大叙事之间的错综复杂的关系。这本书实质上主张将研究焦点从信息(基因)转向真正赋予生命活力的化学过程。

Hacker News上的一篇帖子讨论了Nick Lane的新书《Transformer: The Deep Chemistry of Life and Death》。评论者们争论书名是否试图利用“Transformer”(转换器)概念的流行度来进行SEO优化。一些用户为书名辩护,认为它准确地反映了本书关注生物过程中分子转化的主题。 读者们称赞Lane的生物化学专业知识以及他使复杂主题引人入胜的能力,并推荐了他的早期作品《Power, Sex, and Suicide》作为良好的入门读物。一位评论者将这本书描述为对进化史、生物体能量处理和克雷布斯循环的引人入胜的探索。他们将本书的深度与Siddhartha Mukherjee的作品相比较,并强调Lane关注的是无机物到有机物的转化。总的来说,这本书推荐给对生物学或化学感兴趣的人,尽管一位用户批评这篇评论缺乏细节。

原文

What brings the Earth to life, and our own lives to an end?

For decades, biology has been dominated by information – the power of genes. Yet in terms of information, there is no difference between a living cell and one that died a moment ago. What really animates cells and sets them apart from non-living matter? This question goes back to the flawed geniuses and heroic origins of modern biology. The answer could turn our picture of life on Earth upside down.

In Transformer, Nick Lane captures a scientific renaissance that is hiding in plain sight. At its core is a cycle of reactions that transforms inorganic molecules into the building blocks of life, and the reverse – the iconic Krebs cycle that sits at the heart of metabolism. This conflicted merry-go-round of energy and matter has long taunted true understanding. Nick Lane is in the vanguard of scientists now tracing its ramifications across the tree of life.

To grasp the Krebs cycle is to fathom the deep coherence of biology. It connects the first photosynthetic bacteria with our peculiar cells. It links the emergence of consciousness with the inevitability of death. And it puts the subtle differences between individuals in the same grand story as the rise of the living world itself.

Life is at root a chemical phenomenon: this is its deep logic.

Published by Profile Books

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