A Hacker News thread discusses a study linking cannabis use to major cardiovascular events. Concerns are raised about the study's data accessibility and lack of specificity regarding cannabis strains or consumption methods (smoking vs. edibles). Several users share personal experiences with negative side effects like anxiety and panic attacks, especially with increased potency or after heavy use. Some found success managing these issues by starting with low doses and addressing underlying anxieties. Others point out the potential for withdrawal symptoms and the difficulty of quitting. The discussion highlights the need for more research differentiating the effects of smoking versus other consumption methods, the impact of THC vs other cannabinoids, and controlling for factors like nicotine use. While some emphasize that many people have used cannabis for years without ill effects, others warn against dismissing potential risks and downplaying its addictive potential. The overall sentiment reflects a complex and evolving understanding of cannabis and its health implications.