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原始链接: https://news.ycombinator.com/item?id=43678138
一位Hacker News评论员“spoiler”，对一篇关于脂肪组织在减肥后保留肥胖表观遗传记忆（实际上，更容易反弹体重）的文章做出了回应。“spoiler”本人有减肥挣扎的经历，他将这与常见的“新陈代谢缓慢”理解联系起来，并指出专门减掉脂肪的难度。他提到收到朋友发来的关于“脂肪适应”的视频，质疑其科学有效性，并想知道它是否能抵消文章中描述的表观遗传效应。这位评论员建议进一步探索脂肪适应，作为减轻维持减肥长期挑战的一种潜在策略。
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It always did feel like it was easier to gain weight than lose it, especially fat weight and not muscle weight for me.
I was recently sent a video about fat adaptation (basically teaching your body to be better at burning fat) by a very fit friend, but I wonder how much of that is bro science and how much of it is grounded in reality. Maybe worth looking into more deeply if it can counteract or balance out this.
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